A Proteome-Calibrated Mechanistic Digital Twin of the Glioblastoma Astrocyte Derived from Patient Multi-Omic Data
Mayfield JD. · bioRxiv · 2026-04-23
蛋白质组校准的GBM星形细胞机制性数字孪生（预印本）。
标签：机制与基于主体的模型
共 6 条，按时间倒序。
Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories.
Johnson JAI et al. · Cell · 2025-07-26
可解释“语法”驱动的多细胞主体模型，降低虚拟细胞实验室门槛（含肿瘤示例）。
Mapping the spatial architecture of glioblastoma from core to edge delineates niche-specific tumor cell states and intercellular interactions
Khan SM et al. · bioRxiv · 2025-04-04
GBM核心到边缘的空间结构。
A method for in silico exploration of potential glioblastoma multiforme attractors using single-cell RNA sequencing.
Vieira Junior MG, de Almeida Côrtes AM, Gonçalves Carneiro FR, Carels N, Silva FABD. · Scientific reports · 2024-10-29
基于单细胞数据的GBM吸引子计算探索。
A simple agent-based hybrid model to simulate the biophysics of glioblastoma multiforme cells and the concomitant evolution of the oxygen field.
Saucedo-Mora L, Sanz MÁ, Montáns FJ, Benítez JM. · Computer methods and programs in biomedicine · 2024-01-26
GBM细胞生物物理主体模型。
Virtual and real brain tumors: using mathematical modeling to quantify glioma growth and invasion.
Swanson KR, Bridge C, Murray JD, Alvord EC. · Journal of the neurological sciences · 2003-12-01
Swanson等：“虚拟脑肿瘤”经典增殖-侵袭模型。