paper论文Brain tumor脑肿瘤✓ Verified已核验VC0132

Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations

scFOCAL/ISOSCELES links GBM cell states to L1000 signatures; predicts state-specific sensitivity and OLIG2i+Depatux-M combo.scFOCAL/ISOSCELES:把GBM细胞状态接到L1000药签,预测状态敏感度并验证OLIG2抑制剂+Depatux-M。

Authors / organisation作者 / 机构
Suter et al.
Venue发表于
Nature Communications
Date日期
2026-01-07
Type类型
paper论文
Year年份
2026
DOI
10.1038/s41467-025-67783-5
Verification核验来源
Crossref

GBMscRNA-seqL1000drug-responseISOSCELESscFOCAL

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