Drug and single-cell gene expression integration identifies sensitive and resistant glioblastoma cell populations
scFOCAL/ISOSCELES links GBM cell states to L1000 signatures; predicts state-specific sensitivity and OLIG2i+Depatux-M combo.scFOCAL/ISOSCELES:把GBM细胞状态接到L1000药签,预测状态敏感度并验证OLIG2抑制剂+Depatux-M。
- Authors / organisation作者 / 机构
- Suter et al.
- Venue发表于
- Nature Communications
- Date日期
- 2026-01-07
- Type类型
- paper论文
- Year年份
- 2026
- DOI
- 10.1038/s41467-025-67783-5
- Verification核验来源
- Crossref
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