paper论文Partly relevant部分相关✓ Verified已核验VC0019
Adduri AK et al. · Cell · 2026-08-31
State (Arc Institute): state-embedding + transition model across 70 contexts; Cell 2026.Arc的State模型：跨70种细胞情境预测扰动反应（Cell 2026）。
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news新闻✓ Verified已核验VC0104
Arc Institute · Arc news · 2025-06
Announcement of State (~170M observational + 100M perturbed cells).Arc发布State模型新闻。
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paper论文✓ Verified已核验VC0002
Roohani YH et al. · Cell · 2025-06-01
Arc Institute perspective launching the Virtual Cell Challenge as a 'Turing test' for virtual cells.Arc研究所发起虚拟细胞挑战赛，作为虚拟细胞的“图灵测试”。
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org机构✓ Verified已核验VC0103
Arc Institute · web · date n/a日期未注明
Arc's program combining Perturb-seq data generation, State, and the Challenge.Arc虚拟细胞计划。
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conference会议✓ Verified已核验VC0125
Keystone Symposia · Banff, Canada (to Feb 18) · 2027-02-15
Keystone 2027 single-cell/spatial/perturbation meeting.Keystone 2027单细胞会议。
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preprint预印本✓ Verified已核验VC0139
Metzner E, Guruvayurappan K, Southard KM, Ardy RC, Dey KK, Norman TM. · bioRxiv · 2026-10-12
Norman/Dey labs (MSKCC): CRISPRa Multiome Perturb-seq of 119 TFs + dual-guide Perturb-seq of 1,225 TF pairs in RPE-1; chromatin priming predicts emergent states; Mosaic (Transformer) predicts TF-pair interaction residuals (r=0.484) and nominated a validated triple-TF combination.Norman/Dey 实验室（MSKCC）：在 RPE-1 中对 119 个 TF 做 CRISPRa Multiome Perturb-seq、对 1,225 个 TF 对做双向导 Perturb-seq；染色质预激活可预测新兴状态；Mosaic（Transformer）预测 TF 对相互作用残差（r=0.484），并提名经实验验证的三 TF 组合。
DOI