{"id":"VC0055","type":"preprint","title":"Multimodal Benchmarking of Foundation Model Representations for Cellular Perturbation Response Prediction","authors_or_org":"Hasanaj E, Cole E, Mohammadi S, Addagudi S, Zhang X, Song L, Xing EP.","date":"2025-06-28","year":"2025","venue":"bioRxiv","url":"https://doi.org/10.1101/2025.06.26.661186","doi":"10.1101/2025.06.26.661186","pmid":"","brain_tumor_focus":"no","tags":["benchmark","multimodal"],"tag_slugs":["benchmark"],"tag_labels":["Benchmark & validation"],"tag_labels_zh":["基准评测与验证"],"unmapped_tags":["multimodal"],"one_line_summary_en":"Multimodal benchmarking of FM representations for perturbation response.","one_line_summary_zh":"多模态基础模型表示的扰动预测基准。","verified":"yes","verification_source":"Europe PMC","page_url":"https://gliostate.com/library/VC0055/","api_url":"https://gliostate.com/api/items/VC0055.json","sameAs":["https://doi.org/10.1101/2025.06.26.661186"],"is_preprint":true,"facets":{"type":"https://gliostate.com/library/type/preprint/","year":"https://gliostate.com/library/year/2025/","tags":["https://gliostate.com/library/tag/benchmark/"]},"cited_by":[],"related":[{"id":"VC0058","title":"Virtual Cell Challenge 2026: Benchmarking zero-shot generalization across cellular contexts.","shared_tags":["benchmark"],"page_url":"https://gliostate.com/library/VC0058/","api_url":"https://gliostate.com/api/items/VC0058.json"},{"id":"VC0054","title":"An Empirical Comparison of Virtual Cell Models: Perturbation Prediction, Representation, and the Baseline Gap","shared_tags":["benchmark"],"page_url":"https://gliostate.com/library/VC0054/","api_url":"https://gliostate.com/api/items/VC0054.json"},{"id":"VC0053","title":"Signal, Bounds, and Baselines: Principles for Evaluating Virtual Cell Perturbation Models","shared_tags":["benchmark"],"page_url":"https://gliostate.com/library/VC0053/","api_url":"https://gliostate.com/api/items/VC0053.json"},{"id":"VC0034","title":"scPRINT-2: Towards the next-generation of cell foundation models and benchmarks","shared_tags":["benchmark"],"page_url":"https://gliostate.com/library/VC0034/","api_url":"https://gliostate.com/api/items/VC0034.json"},{"id":"VC0004","title":"AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential.","shared_tags":["benchmark"],"page_url":"https://gliostate.com/library/VC0004/","api_url":"https://gliostate.com/api/items/VC0004.json"},{"id":"VC0052","title":"Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation.","shared_tags":["benchmark"],"page_url":"https://gliostate.com/library/VC0052/","api_url":"https://gliostate.com/api/items/VC0052.json"}]}